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Results 1 to 25 of 46

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Increasing hippocampal neurogenesis: A novel mechanism for antidepressant drugs : Antidepressant Drug DesingMALBERG, Jessica E; SCHECHTER, Lee E.Current pharmaceutical design. 2005, Vol 11, Num 2, pp 145-155, issn 1381-6128, 11 p.Article

The effects of systemic and local microinjection into the central nervous system of the selective serotonin 5-HT6 receptor agonist WAY-208466 on sleep and wakefulness in the ratMONTI, Jaime M; JANTOS, Héctor; SCHECHTER, Lee E et al.Behavioural brain research. 2013, Vol 249, pp 65-74, issn 0166-4328, 10 p.Article

From menarche to menopause : Exploring the underlying biology of depression in women experiencing hormonal changesDEECHER, Darlene; ANDREE, Terrance H; SLOAN, Diane et al.Psychoneuroendocrinology. 2008, Vol 33, Num 1, pp 3-17, issn 0306-4530, 15 p.Article

Acute lecozotan administration increases learning and memory in rats without affecting anxiety or behavioral depressionSKIRZEWSKI, Miguel; HERNANDEZ, Luis; SCHECHTER, Lee E et al.Pharmacology, biochemistry and behavior. 2010, Vol 95, Num 3, pp 325-330, issn 0091-3057, 6 p.Article

A novel approach for predicting antidepressant-induced sexual dysfunction in ratsSUKOFF RIZZO, Stacey J; SCHECHTER, Lee E; ROSENZWEIG-LIPSON, Sharon et al.Psychopharmacologia. 2008, Vol 195, Num 4, pp 459-467, issn 0033-3158, 9 p.Article

Studying rat brain neurochemistry using nanoprobe NMR spectroscopy: A metabonomics approachKHANDELWAL, Purnima; BEYER, Chad E; QIAN LIN et al.Analytical chemistry (Washington, DC). 2004, Vol 76, Num 14, pp 4123-4127, issn 0003-2700, 5 p.Article

α2A-adrenoceptors enhance the serotonergic effects of fluoxetineBEYER, Chad E; QIAN LIN; ROSENZWEIG-LIPSON, Sharon et al.European journal of pharmacology. 2006, Vol 539, Num 3, pp 164-167, issn 0014-2999, 4 p.Article

Antidepressant and anxiolytic effects of selective 5-HT6 receptor agonists in ratsCARR, Gregory V; SCHECHTER, Lee E; LUCKI, Irwin et al.Psychopharmacologia. 2011, Vol 213, Num 2-3, pp 499-507, issn 0033-3158, 9 p.Article

Angiotensin IV elevates oxytocin levels in the rat amygdala and produces anxiolytic-like activity through subsequent oxytocin receptor activationBEYER, Chad E; DWYER, Jason M; PLATT, Brian J et al.Psychopharmacologia. 2010, Vol 209, Num 4, pp 303-311, issn 0033-3158, 9 p.Article

Synthesis and biological evaluation of novel compounds within a class of 3-aminochroman derivatives with dual 5-HT1A receptor and serotonin transporter affinityHATZENBUHLER, Nicole T; EVRARD, Deborah A; QIAN LIN et al.Journal of medicinal chemistry (Print). 2006, Vol 49, Num 15, pp 4785-4789, issn 0022-2623, 5 p.Article

Regulators of G-protein signaling 4: modulation of 5-HT1A-mediated neurotransmitter release in vivoBEYER, Chad E; GHAVAMI, Afshin; QIAN LIN et al.Brain research. 2004, Vol 1022, Num 1-2, pp 214-220, issn 0006-8993, 7 p.Article

1,2,5-Thiadiazole derivatives are potent and selective ligands at human 5-HT1A receptorsSABB, Annmarie L; VOGEL, Robert L; KELLY, Michael G et al.Bioorganic & medicinal chemistry letters (Print). 2001, Vol 11, Num 8, pp 1069-1071, issn 0960-894XArticle

Novel 1-aminoethyl-3-arylsulfonyl-1H-pyrrolo[2,3-b]pyridines are potent 5-HT6 agonistsBERNOTAS, Ronald C; LENICEK, Steven; PING LI et al.Bioorganic & medicinal chemistry. 2009, Vol 17, Num 14, pp 5153-5163, issn 0968-0896, 11 p.Article

Neuropharmacological Profile of Novel and Selective 5-HT6 Receptor Agonists : WAY-181 187 and WAY-208466SCHECHTER, Lee E; QIAN LIN; ROBICHAUD, Albert et al.Neuropsychopharmacology (New York, NY). 2008, Vol 33, Num 6, pp 1323-1335, issn 0893-133X, 13 p.Article

Differential regulation of central BDNF protein levels by antidepressant and non-antidepressant drug treatmentsBALU, Darrick T; HOSHAW, Brian A; MALBERG, Jessica E et al.Brain research. 2008, Vol 1211, pp 37-43, issn 0006-8993, 7 p.Article

Novel pyridyl-fused 3-amino chroman derivatives with dual action at serotonin transporter and 5-HT1A receptorDAHUI ZHOU; HATZENBUHLER, Nicole T; ANDREE, Terrance H et al.Bioorganic & medicinal chemistry letters (Print). 2007, Vol 17, Num 11, pp 3117-3121, issn 0960-894X, 5 p.Article

Increasing the levels of insulin-like growth factor-l by an IGF binding protein inhibitor produces anxiolytic and antidepressant-like effectsMALBERG, Jessica E; PLATT, Brian; SUKOFF RIZZO, Stacey J et al.Neuropsychopharmacology (New York, NY). 2007, Vol 32, Num 11, pp 2360-2368, issn 0893-133X, 9 p.Article

Studies towards the next generation of antidepressants. Part 4: Derivatives of 4-(5-fluoro-1H-indol-3-yl)cyclohexylamine with affinity for the serotonin transporter and the 5-HT1A receptorEVRARD, Deborah A; PING ZHOU; YI, Soo Y et al.Bioorganic & medicinal chemistry letters (Print). 2005, Vol 15, Num 4, pp 911-914, issn 0960-894X, 4 p.Article

1-Sulfonylindazoles as potent and selective 5-HT6 ligandsLIU, Kevin G; LO, Jennifer R; ROBICHAUD, Albert J et al.Bioorganic & medicinal chemistry letters (Print). 2009, Vol 19, Num 9, pp 2413-2415, issn 0960-894X, 3 p.Article

A regiospecific synthesis of a series of 1-sulfonyl azepinoindoles as potent 5-HT6 ligandsLIU, Kevin G; LO, Jennifer R; ROBICHAUD, Albert J et al.Bioorganic & medicinal chemistry letters (Print). 2008, Vol 18, Num 14, pp 3929-3931, issn 0960-894X, 3 p.Article

Studies toward the discovery of the next generation of antidepressants. Part 6: Dual 5-HT1A receptor and serotonin transporter affinity within a class of arylpiperazinyl-cyclohexyl indole derivativesDAHUI ZHOU; PING ZHOU; SMITH, Deborah L et al.Bioorganic & medicinal chemistry. 2008, Vol 16, Num 14, pp 6707-6723, issn 0968-0896, 17 p.Article

N1-arylsulfonyl-3-(1,2,3,6-tetrahydropyridin-4-yl)-1H-indole derivatives are potent and selective 5-HT6 receptor antagonistsCOLE, Derek C; ELLINGBOE, John W; LENNOX, William J et al.Bioorganic & medicinal chemistry letters (Print). 2005, Vol 15, Num 2, pp 379-383, issn 0960-894X, 5 p.Article

Conformationally constrained N1-arylsulfonyltryptamine derivatives as 5-HT6 receptor antagonistsCOLE, Derek C; LENNOX, William J; STOCK, Joseph R et al.Bioorganic & medicinal chemistry letters (Print). 2005, Vol 15, Num 21, pp 4780-4785, issn 0960-894X, 6 p.Article

Advances toward New Antidepressants with Dual Serotonin Transporter and 5-HT1A Receptor Affinity within a Class of 3-Aminochroman Derivatives. Part 2HATZENBUHLER, Nicole T; BAUDY, Reinhardt; MINSHENG ZHANG et al.Journal of medicinal chemistry (Print). 2008, Vol 51, Num 21, pp 6980-7004, issn 0022-2623, 25 p.Article

Discovery of N1 -(6 -chloroimidazo [2,1-b][1,3 ]-thiazole-5-sulfonyl)tryptamine as a potent, selective, and orally active 5-HT6 receptor agonistCOLE, Derek C; STOCK, Joseph R; XIDONG FENG et al.Journal of medicinal chemistry (Print). 2007, Vol 50, Num 23, pp 5535-5538, issn 0022-2623, 4 p.Article

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